Zhi Zhu Selected Research

Nucleotide Aptamers

5/2018	DNA aptamers from whole-cell SELEX as new diagnostic agents against glioblastoma multiforme cells.
6/2016	Evolution of DNA aptamers for malignant brain tumor gliosarcoma cell recognition and clinical tissue imaging.
12/2015	Selection and Application of DNA Aptamer Against Oncogene Amplified in Breast Cancer 1.
1/2015	Evolution of DNA aptamers through in vitro metastatic-cell-based systematic evolution of ligands by exponential enrichment for metastatic cancer recognition and imaging.
10/2014	Selection of DNA aptamers against epidermal growth factor receptor with high affinity and specificity.
7/2014	In vitro selection of DNA aptamers for metastatic breast cancer cell recognition and tissue imaging.
4/2013	Selection of DNA aptamers against epithelial cell adhesion molecule for cancer cell imaging and circulating tumor cell capture.
1/2012	Selection of DNA aptamers against glioblastoma cells with high affinity and specificity.
7/2008	Applications of aptamers in cancer cell biology.

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Zhi Zhu Research Topics

Disease

73	Neoplasms (Cancer) 06/2022 - 10/2002
29	Stomach Neoplasms (Stomach Cancer) 04/2021 - 07/2010
14	Hepatocellular Carcinoma (Hepatoma) 06/2022 - 10/2002
12	Neoplasm Metastasis (Metastasis) 01/2020 - 10/2003
9	Breast Neoplasms (Breast Cancer) 01/2022 - 06/2011
8	Carcinoma (Carcinomatosis) 01/2018 - 07/2010
6	Infections 01/2022 - 10/2002
6	Lymphatic Metastasis 10/2020 - 09/2009
5	Glioma (Gliomas) 01/2022 - 10/2014
5	Circulating Neoplastic Cells 01/2022 - 04/2013
3	Glioblastoma (Glioblastoma Multiforme) 01/2022 - 01/2012
3	Carcinogenesis 01/2019 - 12/2004
3	Leukemia 05/2014 - 07/2008
2	Colonic Neoplasms (Colon Cancer) 06/2022 - 01/2015
2	Bites and Stings (Sting) 12/2021 - 07/2020
2	Communicable Diseases (Infectious Diseases) 10/2021 - 07/2021
2	Squamous Cell Carcinoma (Epidermoid Carcinoma) 11/2020 - 10/2014
2	Cardiovascular Diseases (Cardiovascular Disease) 07/2019 - 11/2018
2	Myocardial Infarction 01/2019 - 08/2017
2	Influenza in Birds (Avian Flu) 04/2018 - 01/2018
2	Triple Negative Breast Neoplasms 01/2018 - 01/2016
2	Adenocarcinoma 04/2017 - 01/2015
2	Brain Neoplasms (Brain Tumor) 06/2016 - 01/2012
2	Herpes Simplex 12/2012 - 03/2011
2	Pancreatic Neoplasms (Pancreatic Cancer) 12/2004 - 05/2004
1	Melanoma (Melanoma, Malignant) 06/2022
1	Ovarian Neoplasms (Ovarian Cancer) 06/2022
1	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 06/2022
1	T-Cell Leukemia (Leukemia, T Cell) 01/2022
1	Metabolic Diseases (Metabolic Disease) 01/2022
1	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2022
1	Sarcoma (Soft Tissue Sarcoma) 01/2022
1	Rectal Neoplasms (Rectal Cancer) 09/2021
1	Fistula 09/2021

Drug/Important Bio-Agent (IBA)

21	Proteins (Proteins, Gene)FDA Link 01/2022 - 10/2002
13	DNA (Deoxyribonucleic Acid)IBA 01/2022 - 08/2009
9	Biomarkers (Surrogate Marker)IBA 01/2021 - 08/2009
9	Biological ProductsIBA 01/2021 - 07/2003
9	Nucleotide AptamersIBA 05/2018 - 07/2008
7	Therapeutic UsesIBA 06/2022 - 03/2011
6	LigandsIBA 01/2022 - 01/2012
6	EnzymesIBA 04/2021 - 03/2011
6	Tumor Biomarkers (Tumor Markers)IBA 01/2016 - 07/2008
6	Phosphotransferases (Kinase)IBA 01/2013 - 07/2010
5	AntigensIBA 12/2021 - 10/2002
4	CalciumIBA 01/2021 - 01/2016
4	Photosensitizing Agents (Photosensitizers)IBA 09/2014 - 06/2012
4	LipofectamineIBA 10/2005 - 10/2003
3	Nucleic AcidsIBA 07/2021 - 10/2012
3	ImmunosorbentsIBA 04/2021 - 11/2018
3	MicroRNAs (MicroRNA)IBA 08/2020 - 01/2018
3	Molecular Probes (Molecular Probe)IBA 01/2018 - 07/2008
3	Pharmaceutical PreparationsIBA 01/2017 - 01/2012
3	HydrogelsIBA 01/2017 - 01/2011
3	Epithelial Cell Adhesion MoleculeIBA 01/2016 - 04/2012
3	Small Interfering RNA (siRNA)IBA 02/2014 - 03/2011
3	Singlet OxygenIBA 11/2013 - 06/2012
3	NucleosidesIBA 05/2012 - 07/2010
2	VaccinesIBA 01/2022 - 01/2020
2	Interleukin-2 (IL2)IBA 12/2021 - 01/2021
2	Catalytic DNA (Deoxyribozyme)IBA 07/2021 - 10/2012
2	B7-H1 AntigenIBA 02/2021 - 01/2020
2	Neoplasm Antigens (Tumor Antigens)IBA 01/2021 - 07/2020
2	MetalsIBA 01/2021 - 10/2012
2	Long Noncoding RNAIBA 11/2020 - 08/2020
2	AntibodiesIBA 07/2020 - 01/2018
2	IonsIBA 01/2020 - 10/2012
2	MyoglobinIBA 01/2019 - 08/2017
2	Sulfhydryl Compounds (Thiols)IBA 01/2019 - 11/2013
2	Transcription Factors (Transcription Factor)IBA 12/2015 - 05/2014
2	Doxorubicin (Adriamycin)FDA LinkGeneric 05/2015 - 05/2011
2	Pyruvic Acid (Pyruvate)IBA 05/2015 - 01/2014
2	phytochlorinIBA 11/2013 - 06/2012
2	1-phenyl-3,3-dimethyltriazene (PDT)IBA 11/2013 - 06/2012
2	ParaffinIBA 07/2013 - 04/2011
2	Formaldehyde (Formol)FDA Link 07/2013 - 04/2011
2	GoldIBA 06/2012 - 06/2012
2	hepatitis B virus X proteinIBA 06/2009 - 10/2002
2	LuciferasesIBA 04/2005 - 10/2003
1	erastinIBA 06/2022
1	Tumor Necrosis Factor InhibitorsIBA 06/2022
1	APTIBA 01/2022
1	Deubiquitinating EnzymesIBA 01/2022
1	Ubiquitin-Specific ProteasesIBA 01/2022
1	Immune Checkpoint ProteinsIBA 12/2021
1	Interleukin-12 (IL 12)IBA 12/2021
1	Granzymes (Granzyme)IBA 12/2021

Therapy/Procedure

25	Therapeutics 01/2022 - 08/2010
11	Drug Therapy (Chemotherapy) 03/2021 - 06/2011
8	Gastrectomy 10/2020 - 02/2014
6	Lymph Node Excision (Lymph Node Dissection) 11/2019 - 06/2012
4	Immunotherapy 06/2022 - 01/2020
3	Neoadjuvant Therapy 09/2021 - 01/2018
2	Chemoradiotherapy 09/2021 - 01/2020
2	Operative Surgical Procedures 06/2018 - 01/2018
2	Photothermal Therapy 11/2013 - 06/2012
2	Photochemotherapy (Photodynamic Therapy) 11/2013 - 06/2012
1	Anesthesia 01/2022
1	Craniotomy 01/2022
1	Colostomy 09/2021